منابع مشابه
Tissue concentrations: do we ever learn?
Over the last decades, numerous papers have appeared--and still are appearing--that describe concentrations in tissues in an effort to predict the efficacy of an antimicrobial agent based on these concentrations and MICs for microorganisms. A common method is to use measurements of concentrations in tissue homogenates, comparing these with values derived from the corresponding blood samples and...
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Although the influence of protein binding (PB) on antibacterial activity has been reported for many antibiotics and over many years, there is currently no standardization for pharmacodynamic models that account for the impact of protein binding of antimicrobial agents in vitro. This might explain the somewhat contradictory results obtained from different studies. Simple in vitro models which co...
متن کاملWhat Do We Learn from Experimental Algorithmics?
Experimental Algorithmics is concerned with the design, implementation , tuning, debugging and performance analysis of computer programs for solving algorithmic problems. It provides methodologies and tools for designing, developing and experimentally analyzing eecient algorithmic codes and aims at integrating and reinforcing traditional theoretical approaches for the design and analysis of alg...
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What makes some metaphors easier to understand than others? Theoretical accounts of metaphor processing appeal to dimensions like conventionality and aptness to explain variability in metaphor comprehensibility. In a typical experiment, one group of naive participants rates a set of metaphoric sentences along these dimensions, while another is timed reading the same sentences. Then, the ratings...
متن کاملHow do we stand?
OBJECTIVE To equip medical practitioners with up-to-date scientific and medical information on the health effects of exposure to fungi in indoor air, clinical evaluation of these health problems, and possible preventive measures. QUALITY OF EVIDENCE MEDLINE was searched from 1985 to 2000 using the MeSH words mould (mold), fungus, indoor air, and health effects. Nearly all studies were case repo...
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ژورنال
عنوان ژورنال: British Journal of General Practice
سال: 2011
ISSN: 0960-1643,1478-5242
DOI: 10.3399/bjgp11x561447